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While the variant Omicron 5 Covid-19 is still dominant in Italy, we are already starting to deal with the next one. The variant was identified in India last May omicron Centaurus (officially BA 2.75) immediately attracted attention and concerns. The first case in our country was sequenced in Sardinia a few days ago, and there are about twenty countries around the world where it was detected. According to a new study, in a few months, however, it could take over the others.
The scenery
After the increase in infections in early summer due to the Omicron 5 variant, currently the most widespread – and responsible, in the United States, for 80 percent of cases – and the beginning of the vaccination campaign for the fourth dose, covid in the last few days is making people talk less about themselves. The attention of the experts, however, is already a lot feared next autumn wavee: according to the authors of one study Italian published onEuropean Journal of Internal Medicine, it could be the latest Indian variant to dominate it. It is – the official name also suggests – a second generation variant, an evolution of the Omicron BA2 variant.
In the study, the researchers focused on the effect of mutations in the BA2.75 variant on human receptors, and they compared it with that of Omicron 5. The results showed that the Indian variant Centaurus is very efficient at binding to human Ace2 receptors, making it potentially able to spread very quickly and, therefore, very contagious. It would be necessary – we read in the article – that the next vaccines were built and adapted precisely on the basis of the latter Omicron sub-variants, in order to solicit an adequate immune response. At the moment, in fact, the ability to neutralize any Omicron variant of the virus after receiving the fourth dose has not been significantly greater when compared with the effectiveness of the third dose.
Can we estimate the aggressiveness of the variant?
In India, at the moment, hospitalization or mortality rates do not appear to have increased following the spread of omicron Centaurus. However, the authors of the study point out, it is still early to say whether it is more aggressive than the previous ones.
“Its effects in terms of aggression are yet to be verified“, He explained to theHandle Fabio Angeli, professor of Cardiovascular Diseases at the University of Insubria and director of the Cardiology of Ics Maugeri in Tradate, co-author of the study. “But the increased ability to bind to our cells and the subsequent paralysis of the Ace2 receptors, which play a fundamental role in regulating our vital capacities, they also make us suppose a probable increased ability to create damage to our organism; this underlines how crucial the new vaccination campaign and the restoration of individual protection measures“.
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